SYSTEMIC REGULATION OF RETINAL MEDIUM-CHAIN FATTY ACID OXIDATION REPLETES TCA CYCLE FLUX IN OXYGEN-INDUCED RETINOPATHY

Systemic regulation of retinal medium-chain fatty acid oxidation repletes TCA cycle flux in oxygen-induced retinopathy

Abstract Activation of anaplerosis takes away glutamine from the biosynthetic pathways to the energy-producing TCA cycle.Especially, induction of hyperoxia driven anaplerosis in neurovascular tissues such as the retina during early stages of development could deplete biosynthetic precursors from newly proliferating endothelial cells impeding physio

read more

When public health debates become abusive

Ideally, public health debates are conducted civilly and focus on the evidence and the public good.In practice, many debates deviate markedly from this approach, Curling - Accessories - Miscellaneous for example with personal denigration of opponents.To help assess methods used in public health debates, a classificatory system of ideal types is int

read more

3D Manufacturing of Glass Microstructures Using Femtosecond Laser

The rapid expansion of femtosecond (fs) laser technology brought previously unavailable capabilities to laser material processing.One of the areas which benefited the most due to these advances was the 3D processing of transparent dielectrics, namely glasses and crystals.This review is dedicated to overviewing the significant advances in the field.

read more